Usefulness of Streptococcus pneumoniae Antigen Detection Kit for the Management of Acute Otitis Media

• Yamanaka Noboru

  Department of Otolaryngology-Head and Neck Surgery, Wakayama Medical University

• Sugita Rinya

  Sugita ENT Clinic

• Fujimaki Yutaka

  Fujimaki ENT Clinic

• Kamide Yosuke

  Kamide ENT Clinic

• Uno Yoshifumi

  Uno ENT Clinic

• Matsubara Shigenori

  Matsubara ORL Clinic

• Uchizono Akihiro

  Sendai ENT Clinic

• Kanesada Keiko

  Nonohana ENT Clinic

• Sawada Shoichi

  Sawada ENT Clinic

• Yamauchi Kazuma

  Department of Otolaryngology-Head and Neck Surgery, Wakayama Medical University

• Togawa Akihisa

  Department of Otolaryngology-Head and Neck Surgery, Wakayama Medical University

• Hotomi Muneki

  Department of Otolaryngology-Head and Neck Surgery, Wakayama Medical University

書誌事項

タイトル別名

• Usefulness of <i>Streptococcus pneumoniae</i> Antigen Detection Kit for the Management of Acute Otitis Media

抄録

A multi-center study was conducted in 8 otolaryngological clinics in Japan to obtain the clinical usefulness of Streptococcus pneumoniae antigen detection kit for the management of acute otitis media (AOM). Children with acute otitis media who visited the clinics in this group study were categorized in terms of severity based on the Clinical Practice Guidelines for Pediatric Acute Otitis Media (2009 Edition), and patients with moderate or severe AOM were given diagnostic tests with S. pneumoniae kit (HS kit). The treatment strategy was decided by each clinic in accordance with its clinic-specific criteria. Study results from clinics that made decisions based on the current treatment guidelines (non-HS group) and in reference to the test kit results (HS group) were stratified and post analysis was performed. The usefulness of the HS kit was evaluated based on the rate of concordance with cultivation tests, the clinical course and the impression of the attending doctors regarding the usefulness. The performance of the kit in comparison to cultivation tests showed a sensitivity of 78.2% and specificity of 89.9%. The results demonstrated that in 127 of 155 subjects (81.9%) the HS kit was “extremely useful” or “useful” in identifying the infecting organism, selecting appropriate antibacterial agents, or in giving the information to explain to patients’ guardians about the management of AOM. In HS kit-positive cases, the HS group and non-HS group judged that the kits were “extremely useful” or “useful” in 97% and in 90%, respectively. On the study of reasons on judging the HS kit as useful, the HS group indicated that the kit was useful in identifying the infecting organism, selecting appropriate antibacterial agents, and in giving the information to explain to patients’ guardians about the management of AOM. On the other hand, the non-HS group considered the kit as useful mainly in identifying the infecting organism.<br>Based on these results, the implementation of a rapid diagnostic method using S.pneumoniae kit was confirmed as highly useful for the management of AOM.

収録刊行物

• 耳鼻咽喉科臨床　補冊

  耳鼻咽喉科臨床　補冊 140 (0), 14-15, 2014

  耳鼻咽喉科臨床学会

キーワード

• <i>Streptococcus pneumoniae</i> antigen detection kit
• acute otitis media
• Streptococcus pneumoniae
• clinical practice guideline

詳細情報

• CRID: 1390001204325559552
• NII論文ID: 130004707418
• DOI: 10.5631/jibirinsuppl.140.14
• ISSN: 21851557
• ISSN: 09121870
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可