Individuality of cerebral blood flow autoregulation in rats confirmed by mathematical model simulation of brain blood vessels

• Nakamura Kazuhiro

• Kondoh Yasushi

• Mizusawa Shigenori

• Kinoshita Toshibumi

Bibliographic Information

Other Title

• 平滑筋機械モデルシミュレーションによるラット脳血流量自動調節能個体差の検討

Abstract

Several reports showed cerebral blood flow (CBF) autoreguration was not persistent. The individual responses of autoreguration in rats might be interpreted by a mathematical model of rat brain blood vessels. We have run a simulation of the mathematical model reported by Ursino. The parameters of the simulation were fitted for experimental results on rats. The simulation shows a variation of CBF autoregulation with a parameter of arteriole in the physiological range. It might be indicated CBF autoregulatory curve was distinct in rats.

Journal

• Cerebral Blood Flow and Metabolism (Japanese journal of cerebral blood flow and metabolism)

  Cerebral Blood Flow and Metabolism (Japanese journal of cerebral blood flow and metabolism) 25 (2), 43-49, 2014

  The Japanese Society of Cerebral Blood Flow and Metabolism

Keywords

• CBF
• CBF autoregulation
• simulation
• myogenic response
• rat

Details

• CRID: 1390001205756213504
• NII Article ID: 130004708199
• DOI: 10.16977/cbfm.25.2_43
• ISSN: 21887519
• ISSN: 09159401
• Web Site: https://www.jstage.jst.go.jp/article/cbfm/25/2/25_43/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2015176456
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed