本邦における膵移植後患者における悪性腫瘍発生症例の検討  [in Japanese] <i>De novo</i> malignancies after pancreas transplantation in Japan  [in Japanese]

Access this Article

Search this Article

Author(s)

    • 森 正樹 Mori Masaki
    • 大阪大学大学院消化器外科学 Department of Surgery, Graduate School of Medicine, Osaka University
    • 伊藤 壽記 Ito Toshinori
    • 大阪大学大学院消化器外科学|大阪大学大学院生体機能補完医学 Department of Surgery, Graduate School of Medicine, Osaka University|Department of Complementary & Alternative Medicine, Graduate School of Medicine, Osaka University
    • 友國 晃 Tomokuni Akira
    • 大阪大学大学院消化器外科学 Department of Surgery, Graduate School of Medicine, Osaka University
    • 濵 直樹 Hama Naoki
    • 大阪大学大学院消化器外科学 Department of Surgery, Graduate School of Medicine, Osaka University

Abstract

<b>【Background】</b>Long-term immunosuppression is associated with an increased risk of cancer. Especially in pancreas transplantations, more intensive immunosuppression is used than in other organ transplantations because of strong immunogenicity. The aim of this studywas to analyze the incidence of <i>de novo</i> malignancies after pancreas transplantations in Japan.<br><b>【Methods】</b>Posttransplant patients with <i>de novo</i> malignancies were surveyed and characterized.<br><b>【Results】</b>Among 107 cases receiving a pancreas transplantation in Japan from 2001 to 2010, <i>de novo</i> malignancy developed in 9 cases; posttransplant lymphoproliferative disorder (PTLD) in 6, malignant brain tumor in 1, renal cell carcinoma in 1, and colon cancer in 1.<br><b>【Conclusions】</b>We clarified the incidence of <i>de novo</i> malignancies after pancreas transplantation in Japan.

Journal

  • Japanese Journal of Transplantation

    Japanese Journal of Transplantation 49(4-5), 348-352, 2014

    The Japan Society for Transplantation

Codes

  • NII Article ID (NAID)
    130004709654
  • Text Lang
    JPN
  • ISSN
    0578-7947
  • Data Source
    J-STAGE 
Page Top