持続灌流装置(LifePort)による障害腎・膵の保存・搬送に関する実験的研究
書誌事項
- タイトル別名
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- Efficacy of hypothermic machine perfusion for preservation of canine kidney and pancreas with warm ischemia
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We studied the efficacy of perfusion preservation for ischemically damaged kidney and pancreas using a newly designed handy perfusion maghine LifePort. Using Beagle dogs, kidneys or pancreas with 30 minutes warm ischemia were preserved for 24 hours with machine perfusion (LifePort group)or simple cold storage (UW group).LifePort group showed the superiority in kidney preservation evaluated by significantly lower serum creatinine levels and higher recipients survival rate(100% vs. 40%)after autografts as compared to UW group. The advantage of LifePort in pancreas preservation, however, was not found in this pilot study. The results of this study demonstrated that machine perfusion using LifePort may be a potent tool for preservation of ischemically damaged kidneys from non-heart beating donors in Japan.
収録刊行物
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- Organ Biology
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Organ Biology 18 (1), 81-86, 2011
一般社団法人 日本臓器保存生物医学会
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詳細情報 詳細情報について
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- CRID
- 1390001205514143872
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- NII論文ID
- 130004709987
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- ISSN
- 21880204
- 13405152
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可