PREPARATION OF POROUS SPHERICAL HYDROXYAPATITE AGGLOMERATES INTERACTED WITH CYCLODEXTRIN

• ITATANI Kiyoshi

  Department of Materials and Life Sciences, Faculty of Science and Engineering, Sophia University

• IKEGAMI Sayaka

  Department of Materials and Life Sciences, Faculty of Science and Engineering, Sophia University

• HAYASHITA Takashi

  Department of Materials and Life Sciences, Faculty of Science and Engineering, Sophia University

• DAVIES Ian J.

  Department of Mechanical Engineering, Curtin University of Technology

• UMEDA Tomohiro

  Department of Materials and Life Sciences, Faculty of Science and Engineering, Sophia University

• MUSHA Yoshiro

  2nd Department of Orthopaedic Surgery, School of Medicine, Toho University

• KODA Seiichiro

  Department of Materials and Life Sciences, Faculty of Science and Engineering, Sophia University

抄録

Porous spherical hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂: HAp) agglomerates with diameters of approximately 1 µm were prepared by: (i) the spray-pyrolysis of calcium phosphate solution containing 0.5 mol dm^-3 Ca(NO₃)₂, 0.3 mol dm^-3 (NH₄)₂HPO₄, 0.1 - 0.4 mol dm^-3 glutaric acid and concentrated HNO₃ at 600°C, using an ultrasonic vibrator, and then (ii) the burnout of residual carbon resulting from the pyrolysis of glutaric acid upon the heat treatment of the spray–pyrolyzed powder at 900°C for 10 min. Three types of resulting HAp powders were then hydrothermally treated with 1.5 mass% β-cyclodextrin (β-CyD) solution at 120°C for 1 h. The amounts of β-CyD in the resulting HAp agglomerates were found to be in the range of 1.1 to 13.1 mass%. Transmission electron microscopy confirmed the presence of β-CyD not only on the surfaces but also inside the spherical HAp agglomerates. When the HAp powder with 13.1 mass% β-CyD addition was immersed in pure water at 90°C for 1 h, the released amount of β-CyD was as low as 2.1 mass%, indicating the enhanced chemical bonding between β-CyD and HAp, due to the hydrothermal treatment.

収録刊行物

• Phosphorus Research Bulletin

  Phosphorus Research Bulletin 24 54-61, 2010

  日本無機リン化学会

キーワード

• Spray pyrolysis technique
• Porous spherical hydroxyapatite agglomerates
• β-Cyclodextrin
• Chemical bonding

詳細情報

• CRID: 1390001205287693440
• NII論文ID: 130004726107
• DOI: 10.3363/prb.24.54
• ISSN: 18822363
• ISSN: 09184783
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可