A Case of Malignant Lymphoma with Hypercalcemia after Breast Cancer Surgery

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  • Yoshida Takashi
    Department of Breast Surgery, Ota Memorial Hospital
  • Kimura Morihiko
    Department of Breast Surgery, Ota Memorial Hospital
  • Goto Yoshinari
    Department of Breast Surgery, Ota Memorial Hospital
  • Horiguchi Jun
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine
  • Takeyoshi Izumi
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine

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  • 乳癌術後に高カルシウム血症を契機に発見された悪性リンパ腫の１例
  • ニュウガン ジュツゴ ニ コウカルシウム ケツショウ オ ケイキ ニ ハッケン サレタ アクセイ リンパシュ ノ 1レイ

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Abstract

A 52-year-old woman underwent partial mastectomy and axillary lymph-node dissection three years ago. The pathological diagnosis was papillotubular carcinoma and no metastases were found in axillary lymph nodes. Recently, the patient complained of general fatigue, appetite loss and lumbago, and consulted another hospital. Laboratory tests revealed hypercalcemia. CT showed para-aortic lymphadenopathy. The patient was transferred to our hospital. Because of para-aortic lymphadenopathy and the high level of soluble interleukin-2 receptor in serum, we suspected malignant lymphoma. After hypercalcemia was improved following administration of zoledronic acid hydrate and elcatonin, the patient was transferred to the department of hematology in another hospital. By cervical lymph node biopsy, the diagnosis was a CD5-positive diffuse large B-cell lymphoma. The patient was treated with chemotherapy, but died seven months later.

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