ラクナ梗塞検出のためのカーネル固有空間テンプレートマッチング

  • 村川 彩希
    熊本大学大学院保健学教育部
  • 谷河 文香
    岐阜大学工学部応用情報学科 東海旅客鉄道株式会社
  • 内山 良一
    熊本大学大学院生命科学研究部先端生命医療科学部門
  • 村松 千左子
    岐阜大学大学院医学系研究科知能イメージ情報分野
  • 原 武史
    岐阜大学大学院医学系研究科知能イメージ情報分野
  • 藤田 広志
    岐阜大学大学院医学系研究科知能イメージ情報分野

書誌事項

タイトル別名
  • Kernel Eigenspace Template Matching for Detection of Lacunar Infarcts on MR Images
  • ラクナ コウソク ケンシュツ ノ タメ ノ カーネル コユウ クウカン テンプレートマッチング

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抄録

Detection of lacunar infarcts is important because their presence indicates an increased risk of severe cerebral infarction and dementia. However, accurate identification of lacunar infarcts is often difficult for radiologists. Our previous computer-aided detection (CAD) scheme achieved a sensitivity of 96.8% with 0.76 false positives (FPs) per slice. However, further reduction of FPs remained an issue for the clinical application. The purpose of this study is to improve our CAD scheme by using kernel eigenspace template matching. First, we selected the regions of interest (ROIs) around the candidate regions detected in our previous method. A kernel eigenspace was then made by using kernel principal component analysis of the training data set. A test ROI was projected onto the same kernel eigenspace as the training data set. The cross-correlation coefficients between the test ROI and all the training ROIs were calculated on the kernel eigenspace. By comparing the two maxima of coefficients with a lacunar ROI and an FP ROI, the test ROI was classified. By using the proposed method, the quantity of the templates became 1.9% of that in template matching on the real space and 31. 9% of FPs could be eliminated while keeping the same sensitivity; nevertheless 30.3% of FPs were eliminated when we employed the eigenspace template matching under the same condition. Therefore, kernel eigenspace template matching could improve FP rate without a significant reduction in the true positive rate.

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