北海道大学病院口腔内科における味覚障害患者210例の臨床的検討 Clinical study of 210 cases of taste disorder
We performed a retrospective study to elucidate the clinical characteristics of taste disorders in patients attending our dental clinic. Subjects comprised 210 outpatients (54 men, 156 women, mean age 65) that reported taste disorders within the past 4.5 years. Hypogeusia and ageusia were the most common conditions (42%), followed by phantogeusia (39%). The main causes of taste disorders among our patients included idiopathic taste disturbance (27%), oral diseases (26%) and psychogenic taste disturbance (25%). Oral diseases involved oral candidiasis (57%) and oral dryness (25%). Treatment mainly consisted of drug therapy; patients with idiopathic and psychogenic taste disturbance were treated with ethyl loflazepate, and patients with zinc deficiency were treated with polaprezinc. The overall improvement rate of symptoms was 61%. Patients with oral disease showed good response (90% improvement rate) to therapy.<br>Since this study showed that taste disorders in several patients were caused by various oral diseases, dentists should be aware that oral diseases such as oral candidiasis and oral dryness can lead to taste disorders, most of which respond well to dental management.
日本口腔科学会雑誌 62(4), 247-253, 2013