A CASE OF EOSINOPHILIC ESOPHAGITIS COMPLICATED WITH CROHN'S DISEASE

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  • クローン病に合併した好酸球性食道炎の1例

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Abstract

A 29-year-old man who had received a diagnosis of Crohn's disease (CD) in 2001 was referred to our department because of relapse of CD. Upper gastrointestinal endoscopy revealed white stipple-like exudates and red linear furrows in the esophagus, and pathological examination of biopsied specimens showed infiltration of eosinophils which was confirmed by the presence of more than 20 eosinophils in every high-power field. Eosinophilic esophagitis (EoE) was suspected ; however, only treatment for CD was started, because the patient was asymptomatic for EoE with no dysphagia, food impaction nor heartburn. After induction of remission of CD, the patient developed food impaction and heartburn without a change in endoscopic and pathological findings. Therefore, the diagnosis of EoE was confirmed. Swallowed fluticasone therapy was provided for 8 weeks. The patient's symptoms improved immediately, and the endoscopic and histologic findings improved as well. EoE in patients with CD is very rare.

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