Usefulness of Cetirizine Hydrochloride (Zyrtec) for Senior with Pruritus or Asteatotic Eczema

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  • SHINDO Masahisa
    Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University
  • YAMADA Nanako
    Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University
  • YAMAMOTO Osamu
    Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University

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Other Title
  • 高齢者の皮膚そう痒症および皮脂欠乏性湿疹に対するセチリジン塩酸塩（ジルテック錠）の有用性の検討
  • 治療 高齢者の皮膚掻痒症および皮脂欠乏性湿疹に対するセチリジン塩酸塩(ジルテック錠)の有用性の検討
  • チリョウ コウレイシャ ノ ヒフソウヨウショウ オヨビ ヒシ ケツボウセイ シッシン ニ タイスル セチリジン エンサンエン ジルテックジョウ ノ ユウヨウセイ ノ ケントウ

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Abstract

To assess the usefulness of cetirizine hydrochloride (Zyrtec®), for senior over 65years-old with pruritus or asteatotic eczema, we investigated the efficacy and safety of cetirizine administration. Significant improvement of itching and improvement of scratch was maintained for 2 weeks and 4 weeks after treatment with cetirizine. There are no adverse events. All cases were useful on general evaluation. Patients were treated with 10 mg/day of cetirizine hydrochloride for 2 weeks. Those in whom the drug showed insufficient efficacy then received treatment at 20 mg/day for another 2 weeks. As a result, increasing the dose of cetirizine maintained significant improvement of the symptom and general improvement. 76% of the patients reported that usual dose, 10 mg/day, of cetirizine for 2 weeks improved the symptom. Total 89% of the patients improved the symptom after increasing the dose of cetirizine on insufficient case. The cetirizine hydrochloride seems safe and useful drug without serious side effect.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 73 (1), 69-76, 2011

    Western Division of Japanese Dermatological Association

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