A Consideration on the Role of HSP70 Appearing in the Periodontal Tissues due to Experimental Orthodontic Force

• Muraoka Rina

  Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Orthodontics, Matsumoto Dental University School of Dentistry

• Nakano Keisuke

  Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Oral Pathology, Matsumoto Dental University School of Dentistry

• Matsuda Hirokazu

  Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Orthodontics, Matsumoto Dental University School of Dentistry

• Tomoda Maki

  Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Orthodontics, Matsumoto Dental University School of Dentistry

• Okafuji Norimasa

  Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine

• Yamada Kazuhiro

  Department of Orthodontics, Matsumoto Dental University School of Dentistry Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine

• Kawakami Toshiyuki

  Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine

Bibliographic Information

Other Title

• 実験的歯科矯正力により歯根膜組織に発現するＨＳＰ７０の役割に関する一考察

Abstract

We examined immunohistochemical expressions of HSP70 and p-HSP70 in the orthodontic periodontal tissues. In the control group, the HSP70 and p-HSP70 expression was observed in the periodontal ligament fibroblasts and that was kept in low levels. In the experimental group, the strong expression of HSP70 was detected according to over time. However, p-HSP70 expression was a bit delayed. The data suggests that HSP70 has been closely involved in the repair of tissue to maintain homeostasis of the periodontal tissues by the activation of periodontal ligament fibroblasts. Farthermore, the data also suggests that HSP70 act as a molecular chaperone of osteogenesis through an activation of osteoblasts.

Journal

• Journal of Hard Tissue Biology

  Journal of Hard Tissue Biology 20 (4), 275-282, 2011

  THE SOCIETY FOR HARD TISSUE REGENERATIVE BIOLOGY

Keywords

• Heat Shock Protein
• HSP70
• Periodontal tissues
• Orthodontic mechanical stress
• Orthodontic tooth movement

Details

• CRID: 1390282679436414464
• NII Article ID: 130004848367
• NII Book ID: AA11074332
• DOI: 10.2485/jhtb.20.275
• ISSN: 1880828X
• ISSN: 13417649
• Web Site: https://mdu.repo.nii.ac.jp/records/2786
• Web Site: https://search.jamas.or.jp/link/ui/2012162420
• Text Lang: ja
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed