Immunohistochemical Observation of Osterix Appearing in the Mouse Orthodontic Periodontal Tissues

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  • Matsuda Hirokazu
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Orthodontics, Matsumoto Dental University School of Dentistry
  • Harada Toshihisa
    Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Muraoka Rina
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Orthodontics, Matsumoto Dental University School of Dentistry
  • Tomoda Maki
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Orthodontics, Matsumoto Dental University School of Dentistry
  • Okafuji Norimasa
    Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine

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  • 歯科矯正力によりマウス歯周組織に発現するOsterixの免疫組織化学的観察

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Abstract

The purpose of the study is to investigate the expression of Osterix in the mouse orthodontic periodontal tissues using Waldo method. Immunohistochemecally in the control group, without experimental orthodontic mechanical stress, there was almost negative and/or quietly weekly positive reactions in the periodontal tissues. In the experimental group after 9 hours, orthodontic tension sties react positively. The positive reactions became stronger over time. The result suggest that Osterix expression in the orthodontic periodontal tension sides act as one of the key factors of osteagenic cell differentiatim.

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