Expression of Chromogranin A in the Mouse Dental Pulp and Periodontal Tissues

  • Sato Masahiro
    Department of Operative Dentistry and Endodontics, Matsumoto Dental University School of Dentistry
  • Nakano Keisuke
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Oral Pathology, Matsumoto Dental University School of Dentistry
  • Saito Shinnosuke
    Oral Health Analysis Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Nabeyama Atsushi
    Oral Health Analysis Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Okafuji Norimasa
    Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Yamamoto Akio
    Department of Operative Dentistry and Endodontics, Matsumoto Dental University School of Dentistry Oral Health Analysis Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Kasahara Etsuo
    Department of Operative Dentistry and Endodontics, Matsumoto Dental University School of Dentistry
  • Hasegawa Hiromasa
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Department of Oral Pathology, Matsumoto Dental University School of Dentistry
  • Kawakami Toshiyuki
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine

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Other Title
  • Chromogranin Aのマウス歯髄と歯周組織における発現

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Abstract

We examined immunohistochemical expression of Chromogranin A (CgA) in the mouse dental pulp and the periodontal tissues, which exposed to 3 hours immediate teeth separation. In the experimental group, CgA positive staining products were frequently detected in the periodontal fibroblasts and endothelial cells, and also detected in the dental pulp cells. The positive reactions were stronger than that of control specimens. The data suggests that induced expression was due to the mechanical stress of wedge insertion.

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