Antiproliferative Activity of Silver Nanoplates on Human Promyelocytic Leukemia Cell Lines

• Sakaguchi, Tatsuya

• Mine, Kenta

• Kudoh, Fuki

• Kamada, Rui

• Sakaguchi, Kazuyasu

抄録

The physical and chemical properties of silver nanomaterials are highly dependent on their shape and size. Recently, Ag nanoparticles have been reported to be useful for medicinal and pharmaceutical applications including anticancer activity. In this study, we showed that Ag nanoplates possess significantly higher antiproliferative activity on human promyelocytic leukemia cells, HL-60, than spherical nanoparticles. The triangular Ag nanoplates induced apoptosis in the cells and were located in the same subcellular compartment as the spherical Ag nanoparticles.

収録刊行物

• Chemistry Letters

  Chemistry Letters 44 (3), 327-329, 2015-03

  Chemical Society of Japan

キーワード

• General Chemistry

詳細情報

• CRID: 1050845763951781632
• NII論文ID: 130004868407
• DOI: 10.1246/cl.141085
• ISSN: 13480715
• ISSN: 03667022
• HANDLE: 2115/63556
• Web Site: https://academic.oup.com/chemlett/article-pdf/44/3/327/55643835/cl.141085.pdf
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN