Validation of a COPD screening questionnaire and establishment of diagnostic cut-points in a Japanese general population: The Hisayama study

• Tsukuya Go

  Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

• Matsumoto Koichiro

  Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

• Fukuyama Satoru

  Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

• Crawford Bruce

  Adelphi Values, Tokyo, Japan

• Nakanishi Yoichi

  Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

• Ichinose Masakazu

  Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

• Machida Kentaro

  Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

• Samukawa Takuya

  Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

• Ninomiya Toshiharu

  Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

• Kiyohara Yutaka

  Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

• Inoue Hiromasa

  Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Bibliographic Information

Other Title

• Hisayama Pulmonary Physiology Study Group. Validation of a COPD screening questionnaire and establishment of diagnostic cut-points in a Japanese general population: the Hisayama study

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is highly prevalent worldwide. COPD is a treatable disease and it is important to identify COPD subjects, highlighting the need for an efficient screening measure. Although the COPD screening questionnaire (COPD Population Screener, COPD-PS) was developed as a screening tool, its validity is not clear in population-based studies. This study determines the validity of the COPD-PS in the general Japanese population.<br>Methods: All registered residents living in the town of Hisayama aged above 40 were solicited to participate in a health check-up in 2012. All subjects aged 40–79 without physician-diagnosed asthma or lung resection were recruited, and 2357 subjects with the COPD-PS recorded and valid spirometry measurements were analyzed. Persistent airflow obstruction (AO) was defined by post-bronchodilator FEV₁/FVC < 0.7. The sensitivity and specificity of the COPD-PS score for identifying AO was assessed by logistic regression analysis.<br>Results: The prevalence of AO in this population was 6.5%. The overall area under the receiver operating characteristic (ROC) curve for the continuous COPD-PS score was 0.748. A cut-point of 4-points is recommended, resulting in a sensitivity of 67.1% and specificity of 72.9% with an area under the ROC curve of 0.70. The positive predictive value was 14.6% and negative predictive value was 97.0%.<br>Conclusions: The COPD-PS appears to be an adequate measure for large scale screening of possible airflow obstruction requiring further testing with spirometry.

Journal

• Allergology International

  Allergology International 64 (1), 49-53, 2015

  Japanese Society of Allergology

Keywords

• Bronchodilators; Chronic obstructive pulmonary disease; Pulmonary function tests; Questionnaires; Screening

Details

• CRID: 1390282679609090176
• NII Article ID: 130004873118
• DOI: 10.1016/j.alit.2014.06.002
• ISSN: 14401592
• ISSN: 13238930
• Web Site: https://api.elsevier.com/content/article/PII:S1323893014000203?httpAccept=text/plain
• Web Site: https://api.elsevier.com/content/article/PII:S1323893014000203?httpAccept=text/xml
• Web Site: https://search.jamas.or.jp/link/ui/2016025881
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed