ラットヒラメ筋廃用性萎縮に及ぼす間歇的伸張運動の効果:─筋線維タイプおよび長軸部位別の検討─  [in Japanese] Effect of Intermittent Stretching Exercise on the Fiber Types and Muscle Segments of the Rat Soleus Muscle in Disuse Atrophy  [in Japanese]

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Author(s)

    • 上野 勝也 UENO Katsuya
    • やわたメディカルセンター リハビリテーション技師部 Department of Rehabilitation, Yawata Medical Center
    • 久保 あずさ KUBO Azusa
    • 金沢大学大学院 医薬保健学総合研究科|金沢大学付属病院 Graduate School of Medical Sciences , Kanazawa University|Kanazawa University Hospital
    • 宮地 諒 [他] MIYACHI Ryo
    • 金沢大学大学院 医薬保健学総合研究科|石川県済生会金沢病院 リハビリテーション部 Graduate School of Medical Sciences , Kanazawa University|Department of Rehabilitation, Saiseikai Kanazawa Hospital

Abstract

〔目的〕ラットヒラメ筋の廃用性萎縮進行中に間歇的伸張運動を実施し,筋線維タイプ別の筋萎縮抑制効果を長軸部位の視点から検討することを目的とした.〔対象〕Wistar系雄ラットヒラメ筋を対象とした.〔方法〕ラットに対し通常飼育するCON群,廃用性筋萎縮を惹起するHS群,実験期間中,間歇的伸張運動を行うST群の3群を設定.実験期間終了後,対象筋の近位部・中央部・遠位部で切片を作成し,HE染色を行い,ATPase染色を実施し,最後に筋線維横断面積を測定した.〔結果〕,筋線維横断面積はタイプI・II線維とも全ての部位でHS群と比較し有意に高くST群の,中央部,遠位部,近位部の順に高値であった.〔結語〕タイプI・II線維ともに筋萎縮抑制効果がみられ,筋の長軸部位別にその効果が異なることが示唆される. <br>

[Purpose] The purpose is the effects of intermittent stretching exercise on disuse atrophy of the rat soleus muscle with respect to sites and muscle type. [Subjects] Twenty-one 8-week-old male Wistar rats were used. [Methods] The rats were divided into 3 groups: the CON group which received standard breeding, the HS group in which disuse atrophy of the soleus muscle was induced by hind-limb suspension, and the ST group which received intermittent stretching exercise during the hind-limb suspension period. At the end of the suspension period, the soleus muscle was excised and cut into proximal, middle, and distal samples which were stained with hematoxylin-eosin and ATPase. Subsequently, the cross-sectional area (CSA) was measured. [Results] CSAs of both type I and II fibers were significantly higher in the ST group than in the HS group, and the values of the middle region were significantly higher than those of the distal region. Also, the values of the distal region were significantly higher than those of the proximal region. [Conclusion] The results suggest that atrophy of both type I and II fibers of disused muscles is inhibited by stretching, and that there are differences in effect among the longitudinal sites of the rat soleus muscle. <br>

Journal

  • Rigakuryoho Kagaku

    Rigakuryoho Kagaku 30(1), 15-20, 2015

    The Society of Physical Therapy Science

Codes

  • NII Article ID (NAID)
    130004874969
  • NII NACSIS-CAT ID (NCID)
    AN10472896
  • Text Lang
    JPN
  • Article Type
    journal article
  • ISSN
    1341-1667
  • NDL Article ID
    026233985
  • NDL Call No.
    Z7-1893
  • Data Source
    NDL  IR  J-STAGE 
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