HDL-コレステロール値に影響する諸因子に関する統計的検討

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  • Studies on Various Factors Relating to Serum High Density Lipoprotein Cholesterol Levels

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HDL-Cholesterol (HDL-C) level was measured in relatively large number of subjects, and it was compared with other factors which were supposed to be related to serum HDL-C levels. In the present studies, the following results were obtained.<br>(1) HDL-C level was negatively corelated with atherogenic Index, pre-β+β/α ratio, plasma triglyceride levels and obesity Index for both sexes, and positively co-related with plasma PL levels for both sexes, and plasma T. C. and FFA levels for women.<br>(2) While the subjects with both obesity and hypertriglyceridemia demonstrated marked decrease of HDL-C levels, the subjects with only hypertriglyceridemia (not obese) demonstrated relative decrease of HDL-C levels compared with normal subjects. On the contrary, subjects with only obesity (not with hypertriglyceridemia) did not show decrease of HDL-C levels.<br>(3) While mean HDL-C level was significantly higher in the alcoholic subjects and the more the alcoholic intake, the higher the HDL-C level.<br>(4) While mean HDL-C level was significantly lower in the subjects with heavy cigarette smoking, mean triglyceride level was higher in the smoking subjects.<br>(5) The subjects with abnormal electrocardiography (non specific ST, T Change) did not demonstrate decrease of HDL-C level compared with normal subjects.

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