血清脂質値に対する Probucol の効果

• 岡本 良三

  The First Department of Internal Medicine, Kobe University School of Medicine

• 高野 新二

  The First Department of Internal Medicine, Kobe University School of Medicine

• 築谷 学

  The First Department of Internal Medicine, Kobe University School of Medicine

• 末広 厚夫

  The First Department of Internal Medicine, Kobe University School of Medicine

• 羽溪 眞

  The First Department of Internal Medicine, Kobe University School of Medicine

• 藤野 基博

  The First Department of Internal Medicine, Kobe University School of Medicine

• 福崎 恒

  The First Department of Internal Medicine, Kobe University School of Medicine

• 吉田 睦

  Shin-nittetsu Hirohata Hospital

• 初村 利衛

  Ako City Hospital

• 堀 康郎

  Ako City Hospital

• 廣内 恒

  Public Hidaka Hospital

• 今井 直昭

  Public Hidaka Hospital

• 太田 耕治

  National Akashi Hospital

書誌事項

タイトル別名

• Probucol in Hypercholesterolemia A Multiple Open Study

抄録

The effect of Probucol on serum lipids and lipoprotein was studied in 51 patients with primary hypercholesterolemia in multiple open study. After 1 month of placebo period the patients received 4×250mg of Probucol per day for 4 months. Total and VLDL+LDL cholesterol were significantly reduced with Probucol (23-24% and 22-23 respectively). The concentration of serum triglyceride was not significantly altered. The concentration of HDL cholesterol was reduced under Probucol treatment (25-31%). The Total chol-HDL-chol ratio during Probucol was increased (22%). In general, the subjective and objective tolerance of the drug was excellent.

収録刊行物

• 動脈硬化

  動脈硬化 10 (6), 1125-1131, 1983

  Japan Atherosclerosis Society

詳細情報

• CRID: 1572543028268006144
• NII論文ID: 130004882689
• ISSN: 03862682
• Web Site: https://jlc.jst.go.jp/DN/JALC/00169011732?from=CiNii
• データソース種別:
  • CiNii Articles