血中遊離脂肪酸の動態

  • 鴨川 隆彦
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine
  • 南部 征喜
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine
  • 植木 一虎
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine
  • 神元 繁道
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine
  • 万江 治夫
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine
  • 仮屋 純人
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine
  • 緒方 尚子
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine
  • 戸嶋 裕徳
    The 3rd Department of Internal Medicine and Clinical Pathology, Kurume University, School of Medicine

書誌事項

タイトル別名
  • The Significance of Plasma Free Fatty Acids (FFA)

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抄録

50g. oral glucose tolerance test was performed on 18 subjects with moderate obesity to elucidate the significance of FFA response to caloryrestriction in human. The subject were divided into following three groups; (A) with normal glucose tolerance at four weeks during caloryrestriction therapy accompaning with (1) normal response of immunoreactive insulin (IRI) (n=8), (2) high response of IRI to glucose load (n=6). (B) with glucose intolerance (DM type with fasting glucose under 120mg/100ml) at four weeks (n=4).<br>Results; (1) Mean value of maxium decreased FFA (basal FFA) before the diet-therapy was higher in group (B) than in both group (A)-1 and (A)-2, but there was not significant difference in mean value of relative body weight (RBW) and plasma tryglyceride (TG) between groups before the diet therapy. (2) The significantly increased basal FFA and the significantly decreased TG after the diet-therapy was seen in group (A)-2 and in group (A)-1, respectively.<br>These results, especially the increase of basal FFA after calory-restriction seen in the subjects with high response of IRI, might be estimated the different action of insulin between glucose-utilization and inhibition of FFA-release in obese subjects.

収録刊行物

  • 動脈硬化

    動脈硬化 7 (1), 219-224, 1979

    Japan Atherosclerosis Society

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