Advanced Thymic Cancer Treated with Carboplatin and Paclitaxel in a Patient Undergoing Hemodialysis

  • Miura Satoru
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Kagamu Hiroshi
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Sakai Takehito
    Department of Internal Medicine, Saiseikai Niigata Daini Hospital, Japan
  • Nozaki Koichiro
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Asakawa Katsuaki
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Moro Hiroshi
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Okajima Masaaki
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Watanabe Satoshi
    Bioscience Medical Research Center, Niigata University Medical and Dental Hospital, Japan
  • Yamamoto Suguru
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Iino Noriaki
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Goto Shin
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Kazama Junichiro James
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan
  • Yoshizawa Hirohisa
    Bioscience Medical Research Center, Niigata University Medical and Dental Hospital, Japan
  • Narita Ichiei
    Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan

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Abstract

A 53-year-old man with an asymptomatic anterior mediastinal tumor undergoing hemodialysis was referred to our institution. He was diagnosed with thymic basaloid carcinoma based on the findings of a chest tomography-guided biopsy and successfully treated with carboplatin (300 mg/m2/day) and paclitaxel (200 mg/m2/day) on day 1 for six three-week cycles. To our knowledge, this is the first report regarding the efficiency of a carboplatin dose-definition method based on the body surface area with paclitaxel in a hemodialysis patient. This report may therefore be useful for treating hemodialysis patients who are candidates for carboplatin and paclitaxel therapy.<br>

Journal

  • Internal Medicine

    Internal Medicine 54 (1), 55-58, 2015

    The Japanese Society of Internal Medicine

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