胸腺腫大を伴ない甲状腺機能亢進症と血小板減少性紫斑病との合併した1例

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タイトル別名
  • A Case of Thrombocytopenic Purpura with Hyperthyroidism Complicated by Enlarged Thymus
  • キョウセン シュダイ オ トモナイ コウジョウセン キノウ コウシンショウ ト

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抄録

A 37-year-old male was admitted on May 17, 1973, because of purpura over the extremities. As the platelet count was 2000/mm3 and immature-looking megakaryocytes were increased in the bone marrow, a diagnosis of thrombocytopenic purpura was made. The treatment was initiated with corticosteroid which did not effect much and thereafter thrombocytopenia remained. A month after admission, insomnia developed and thyroid functions revealed T3 46.4%, T4 12 μg/dl and BMR+13%. Having an episode of subarachinoidal hemorrhage on Aug. 27, 1974, he was readmitted. The further examinations performed after recovery from this episode, revealed that antithrombocyte antibody was negative, antithyroglobulin antibody 100X positive, antimicrosome antibody negative and LATS negative. Tri-iodothyronin supression test showed poor supression and pneumomediastinography showed the enlarged thymus in the anterior mediastinum. Hyperthyroidism fluctuated from relapse to remission without antithyroid treatment and this fluctuation of the disease seemed to correlate with the dose of corticosteroid. The possible relationship between thrombocytopenic purpura and hyperthyroidism was briefly discussed.

収録刊行物

  • 臨床血液

    臨床血液 18 (1), 66-72, 1977

    一般社団法人 日本血液学会

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