犬アトピー性皮膚炎における<i>Lactobacillus paracasei</i> K71の補助的治療効果  [in Japanese] Complementary Effect of Oral Administration of <i>Lactobacillus paracasei</i> K71 on Canine Atopic Dermatitis  [in Japanese]

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Abstract

犬アトピー性皮膚炎(cAD)における<i>Lactobacillus paracasei</i> K71(K71株)の補助的治療効果を検討した。犬アトピー性皮膚炎(cAD)と診断した5例にプレドニゾロン0.5 mg/kg隔日投与を処方し,3例に試験食乳酸菌(K71株)を,2例に陽性対照セチリジン塩酸塩を併用し,12週間追跡しその補助的治療効果を検討した。皮膚病変の重症度は,獣医師によるCADESI(Canine Atopic Dermatitis Extent and Severity Index)スコア,飼い主による痒みスコア,薬剤ステロイド使用量により評価した。試験終了時全例で皮膚症状の緩和が認められたが,K71株治療群は陽性対照治療群と比較して,CADESIスコア,痒みスコア,ステロイド使用量のいずれも減少する傾向にあった。以上より,K71株はcADの症状緩和に有用と推察された。<br>

We investigated the complementary effect of oral administration of <i>Lactobacillus paracasei</i> K71 (K71) on canine atopic dermatitis (cAD). Five dogs were diagnosed as having cAD and they were treated with prednisolone, 0.5 mg/kg, every other day. Among them, K71 (K71 group) and cetirizine hydrochloride (positive control group) were prescribed as complementary therapy for 12 weeks for three and two dogs, respectively. The change of disease severity of skin symptoms were evaluated with the following three indexes: canine atopic dermatitis extent and severity index (CADESI) scored by the veterinarian, pruritus scored by the owners, and the amount of steroid required. Improvements of skin symptoms were observed in all five cases at the end of investigation. However, all of the indexes in the K71 group were clearly better than those of the positive control group. These results suggest that oral administration K71 is a useful complementary therapy for cAD.<br>

Journal

  • The Japanese Journal of Veterinary Dermatology

    The Japanese Journal of Veterinary Dermatology 19(3), 155-158, 2013

    Japanese Society of Veterinary Dermatology

Codes

  • NII Article ID (NAID)
    130004937869
  • Text Lang
    JPN
  • ISSN
    1347-6416
  • Data Source
    J-STAGE 
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