Bone Response of Collagen- or Laminin-immobilized Screw-type Titanium Implants using Tresyl Chloride-activated Technique

• RAITA Yuki

  Department of Geriatric Dentistry,

• KOMATSU Koichiro

  Department of Pharmacology,

• HAYAKAWA Tohru

  Department of Dental Engineering, Tsurumi University School of Dental Medicine, Yokohama, Japan

抄録

The aim of this study was to evaluate the efficacy of collagen- or laminin-immobilized titanium implant on surrounding bone formation after implantation in a rat molar model. Collagen or laminin was immobilized onto titanium implants using a tresyl chloride-activated technique. The rat first molars were extracted and then the implants were immediately placed in the tooth sockets. At 4 weeks after implantation, undecalcified sections were prepared and bone response around the implants was evaluated. The value of bone to implant contact was significantly greater around the collagen-immobilized implants than around the titanium- and laminin-immobilized ones. It is assumed that immobilized collagen triggered bone formation around the implant material. These results suggest that collagen immobilization accelerates new bone formation.

収録刊行物

• Journal of Oral Tissue Engineering

  Journal of Oral Tissue Engineering 11 (2), 113-122, 2013

  日本再生歯科医学会

キーワード

• collagen
• laminin
• tresyl chloride
• bone response
• crew-type titanium implant

詳細情報

• CRID: 1390001205224632448
• NII論文ID: 130004941103
• DOI: 10.11223/jarde.11.113
• ISSN: 18800823
• ISSN: 13489623
• Web Site: https://search.jamas.or.jp/link/ui/2015113171
• 本文言語コード: en
• データソース種別:
  • JaLC
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可