Assessment of endothelial function. History, methodological aspects, and clinical perspectives

  • Higashi Yukihito
    Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital

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タイトル別名
  • Assessment of Endothelial Function
  • History, Methodological Aspects, and Clinical Perspectives

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抄録

In 1986, endothelial function was measured for the first time in patients with atherosclerotic coronary arteries. Since then, several methods for assessment of endothelial function, such as endothelium-dependent vasodilation induced by intra-arterial infusion of vasoactive agents using coronary angiography, Doppler flow guide wire, mercury-filled Silastic strain-gauge plethysmography, flow-mediated vasodilation, reactive hyperemia-peripheral arterial tonometry, and vascular response using an oscillometric method have been performed in humans. This review focuses on the assessment of endothelial function, including measurement history, methodological issues, and clinical perspectives.

収録刊行物

  • International Heart Journal

    International Heart Journal 56 (2), 125-134, 2015

    一般社団法人 インターナショナル・ハート・ジャーナル刊行会

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