眼内炎症反応の成立と抗原提示過程

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タイトル別名
  • Intraocular Inflammation and Antigen Presentation
  • ガンナイ エンショウ ハンノウ ノ セイリツ ト コウゲン テイジ カテイ

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Intraocular space is thought to be an immune privileged site. One of the most well known facts is that the corneal plantation is successful even if the donor's MHC molecules doesn't match with the recipient's. However, still this doesn't mean that the immune reaction is completely inhibited in the intraocular tissue, since the intraocular herpes infection develops fulminate immune inflammation known as acute retinal necrosis.<br> For explaining these complicated intraocular immune responses, in which some immune reactions are inhibited while others develop immuneinflammation, it is required to study the antigen presenting process in the intraocular tissue. And since there isn't much reports about whether the antigen presentation process in the intraocular tissue takes place or not in this paper we show preliminary results indicating the existence of potential cells able to present antigens. We also review recent literature reporting the immune reactions in intraocular tissue and central nervous systems.<br>

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