眼内炎症反応の成立と抗原提示過程  [in Japanese] Intraocular Inflammation and Antigen Presentation  [in Japanese]

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Author(s)

    • 山木 邦比古 Yamaki Kunihiko
    • 日本医科大学大学院医学研究科感覚器視覚機能医学 Department of Vision and Ophthalmology, Graduate School of Medicine, Nippon Medical School

Abstract

Intraocular space is thought to be an immune privileged site. One of the most well known facts is that the corneal plantation is successful even if the donor's MHC molecules doesn't match with the recipient's. However, still this doesn't mean that the immune reaction is completely inhibited in the intraocular tissue, since the intraocular herpes infection develops fulminate immune inflammation known as acute retinal necrosis.<br> For explaining these complicated intraocular immune responses, in which some immune reactions are inhibited while others develop immuneinflammation, it is required to study the antigen presenting process in the intraocular tissue. And since there isn't much reports about whether the antigen presentation process in the intraocular tissue takes place or not in this paper we show preliminary results indicating the existence of potential cells able to present antigens. We also review recent literature reporting the immune reactions in intraocular tissue and central nervous systems.<br>

Journal

  • Nihon Ika Daigaku Igakkai Zasshi

    Nihon Ika Daigaku Igakkai Zasshi 4(1), 8-14, 2008

    The Medical Association of Nippon Medical School

Codes

  • NII Article ID (NAID)
    130004941905
  • NII NACSIS-CAT ID (NCID)
    AA1200910X
  • Text Lang
    JPN
  • Journal Type
    大学紀要
  • ISSN
    1349-8975
  • NDL Article ID
    9390575
  • NDL Source Classification
    ZS7(科学技術--医学)
  • NDL Call No.
    Z74-E436
  • Data Source
    NDL  J-STAGE 
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