Neurological involvement of relapsing polychondritis in Japan: An epidemiological study

• Suzuki Noboru

  Departments and Institutions: Institute of Medical Science and Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

• Shimizu Jun

  Departments and Institutions: Institute of Medical Science and Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

• Oka Hiroshi

  Departments and Institutions: Institute of Medical Science and Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

• Yamano Yoshihisa

  Departments and Institutions: Institute of Medical Science and Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

• Yudoh Kazuo

  Departments and Institutions: Institute of Medical Science and Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

抄録

We conducted a large scale epidemiological study in Japan and revealed a high mortality rate in RP patients with neurological involvement. Japanese RP patients developed encephalitis/meningitis (12 out of 239 cases, 5.0%), cerebral infarct/bleeding (5 cases, 2.1%) and cerebral vasculitis (4 cases, 1.7%). The mortality rate was 18%, in contrast to 8.1% of RP patients without neurological involvement. We suggested that neurological involvement appeared to be a major determinant of disease severity in patients with RP.

収録刊行物

• Inflammation and Regeneration

  Inflammation and Regeneration 34 (4), 206-208, 2014

  一般社団法人 日本炎症・再生医学会

キーワード

• relapsing polychondritis
• epidemiology
• encephalitis
• meningitis
• cerebral stroke
• auricular cartilage

詳細情報

• CRID: 1390001205257842176
• NII論文ID: 130004943867
• DOI: 10.2492/inflammregen.34.206
• ISSN: 18808190
• ISSN: 18809693
• Web Site: https://search.jamas.or.jp/link/ui/2016090498
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可