Paper-based Diagnostic Devices for Evaluating the Quality of Sperms

• Matsuura Koji

• Chen Kuan-hung

• Tsai Cheng-han

• Li Wenqian

• Asano Yuka

• Keiji Naruse

• Cheng Chao-min

抄録

We have demonstrated an inexpensive but robust and easy-to-handle device for monitoring the health status of human sperm made by patterning a piece of paper and measuring the activity of a specific enzyme. After applying semen to the hydrophilic center circle of our patterned paper, the thizain assay could suggest sperm concentration in semen, and MTT assay data could contribute to estimating the percentage of motile human sperm in semen. Using this paper-based device, we can evaluate fertility levels without consulting doctors, and use our assay to compare results with WHO reference values for sperm concentration (10-20M) and motility (more than 50%).We believe that this paper-based assay system would be useful for fertility checks based on WHO references, without need of a microscope, and at home. Using this assay method, males in developed or developing countries who are reluctant or unable to consult ART clinics can self-analyze their sperm characteristics.

収録刊行物

• 生体医工学

  生体医工学 52 (Supplement), O-551-O-552, 2014

  公益社団法人 日本生体医工学会

詳細情報

• CRID: 1390001205267006464
• NII論文ID: 130004948252
• DOI: 10.11239/jsmbe.52.o-551
• ISSN: 18814379
• ISSN: 1347443X
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可