膵島移植症例登録報告 (2013)

• 日本膵・膵島移植研究会膵島移植班

書誌事項

タイトル別名

• Islet transplantation in Japan
• ―Report from Japanese Islet Transplantation Registry―

抄録

Islet transplantation employing donors after cardiac death (DCD) can relieve glucose instability and problems with hypoglycemia while the graft is functioning. However, islets from DCD might be associated with reduced long-term graft survival. We started the phase II clinical trial with type 1 diabetes patients for islet transplantation using both brain-dead donors and DCD to evaluate ATG induction and TNF inhibition protocol. Primary endpoints are the proportion of subjects with HbA1c＜7.4% and who are free of severe hypoglycemic events one years after the first islet cell infusion. This trial would play a critical role in establishing islet transplantation in Japan.

収録刊行物

• 移植

  移植 48 (6), 384-389, 2013

  一般社団法人 日本移植学会

キーワード

• Japanese Pancreas and Islet Transplantation Association
• clinical trial
• islet transplantation
• type 1 diabetes mellitus

詳細情報

• CRID: 1390282680485889536
• NII論文ID: 130005002790
• DOI: 10.11386/jst.48.384
• ISSN: 21880034
• ISSN: 05787947
• Web Site: https://search.jamas.or.jp/link/ui/2014141013
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可