Bibliographic survey on the clinical application of magnetoencephalography (IV): Psychiatric diseases and dementia

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  • 脳磁図の臨床応用に関する文献レビュー (第4報) : 精神科疾患・認知症
  • ノウジズ ノ リンショウ オウヨウ ニ カンスル ブンケン レビュー(ダイ4ホウ)セイシンカ シッカン ・ ニンチショウ

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Abstract

Magnetoencephalography (MEG) is a powerful tool of basic and clinical neuroscience to detect real neuronal activities directly and non-invasively with good time and spatial resolution. Since the ministry of health in Japan approved MEG as clinical examination covered by health insurance in 2004, many patients suffering from various brain disorders benefitted from this method for these years. We reviewed clinical MEG studies regarding psychiatry diseases and dementia based on a website bibliographic survey before March 2012 on MEDLINE using the keywords of each disease AND (MEG OR magnetoencephalography). We found 95 papers about schizophrenia, 23 about mood disorders, 29 about developmental disorders, 13 about epilepsy psychosis, 71 about dementia. Then, we selected several papers with evidence level higher than 3 to assess the clinical utility of MEG. Although a few studies stressed the superiority of MEG compared to EEG for the diagnosis or treatment indication for psychiatric diseases and dementia, we could not find any papers with evidence level higher than 2 except two about dementia. Future development is needed for more objective analysis of MEG findings in psychiatry diseases and dementia.

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