Manipulation and control of cultured human osteoblast based on micro dynamic stimulation

• Nakamura Takeshi

  Yamagata University

• Kosawada Tadashi

  Yamagata University

• Suzuki Masato

  Yamagata University

• Konno Ken-ichi

  Yamagata University

• Feng Zhonggang

  Yamagata University

Bibliographic Information

Other Title

• 動的マイクロ力学刺激を用いたヒト骨芽細胞の操作・培養コントロール

Abstract

In this study, a new sensor system is developed to detect compliance of cultured cells by using dynamic response of a piezoelectric vibrator. The sensor was integrally controlled by a micromanipulator system, while dimensions and morphologies of the cells were measured by an inverted phase contrast microscope system. Experimental studies have been carried out using normal human osteoblast. The studies have shown the sensor's capability to detect changes of mechanical properties of the cultured cells. Also, the method has shown the relationship between compliance and repolymerization time of the stress fiber.

Journal

• Proceedings of the Japan Joint Automatic Control Conference

  Proceedings of the Japan Joint Automatic Control Conference 51 (0), 104-104, 2008

  The Japan Joint Automatic Control Conference

Keywords

• Dynamic Stimulation
• Micro Sensor-Actuator
• Human Osteoblast
• Cell Culture Control
• Stress Fiber

Details

• CRID: 1390282680623901184
• NII Article ID: 130005024975
• DOI: 10.11511/jacc.51.0.104.0
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed