Facile Synthesis of Deuterium-Labelled Geranylgeraniols
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Facile and stereoselective syntheses of three different kinds of deuterium-labelled geranylgeraniol analogs have been achieved. LiAlD<sub>4</sub> is used as the deuterium source to ensure high deuterium incorporation. [8,8-<i>d</i><sub>2</sub>]- and [9,9-<i>d</i><sub>2</sub>]-geranylgeraniols have been prepared for the first time. [10-<i>d</i>]-geranylgeraniol was efficiently prepared with a high degree of deuterium incorporation.
- Bulletin of the Chemical Society of Japan
Bulletin of the Chemical Society of Japan 88(4), 575-577, 2015
The Chemical Society of Japan