Effects of Biological Responses of Titanium Surfaces Treated with Various Solutions

DOI Open Access
  • HARADA Yasumitsu
    Department of Prosthodontics and Oral Rehabilitation, Graduate School of Dentistry, Kanagawa Dental University
  • OHNO Akinori
    Department of Prosthodontics and Oral Rehabilitation, Graduate School of Dentistry, Kanagawa Dental University
  • HORI Norio
    Department of Prosthodontics and Oral Rehabilitation, Graduate School of Dentistry, Kanagawa Dental University
  • KIMOTO Katsuhiko
    Department of Prosthodontics and Oral Rehabilitation, Graduate School of Dentistry, Kanagawa Dental University

Bibliographic Information

Other Title
  • 溶液浸漬処理後のチタン表面が生物学的応答に及ぼす影響

Search this article

Abstract

A chemical approach to the treatment of the implant surface is critical to promote bone formation around the implant. The aim of this study was to examine and compare the biological responses of a titanium surface treated with various chemical solutions. Titanium disks and cylindrical rods were prepared from commercially-pure titanium with machine turning. Titanium surfaces were treated with NaCl, KCl, CaCl2, and MgCl2 solutions for 3 h. The capacity for protein adsorption and cell attachment was tested on the titanium surface after solution treatment, in vitro, and was examined for its bone-to-implant strength in vivo. In addition, the wettability of each treated titanium surface was examined, and the cell survival rates were verified. In all solution conditions, no significant difference in cell viability and wettability was found. The control solution (pure water) showed no significant differences compared with the treatment groups of NaCl and KCl in protein adsorption and cell attachment capacity. After treatment with CaCl2 or MgCl2 solutions, protein adsorption and cell attachment were increased compared with those achieved with NaCl or KCl solutions. The solution containing Ca or Mg showed better boneimplant strength in vivo. The present results suggest that the titanium surface treated with a solution containing Ca or Mg ions enhanced protein adsorption and cell attachment capacity early and more dramatically for the process of bone formation and increased bone-implant strength in vivo. The solution treatment with divalent cations of Ca or Mg was effective for fabricating titanium implants with enhanced bioactivity and osteoconductivity. Therefore, this chemical treatment of titanium surfaces is a simple and convenient method for improving osseointegration.

Journal

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top