Molecular Simulation Study of Permeability of Molecules through Lipid Membranes

• Shinoda Wataru

  Graduate School of Engineering, Nagoya University

Bibliographic Information

Other Title

• 脂質膜透過現象の分子シミュレーションによる研究
• シシツマク トウカ ゲンショウ ノ ブンシ シミュレーション ニ ヨル ケンキュウ

Abstract

This review presents a brief overview of simulation approach to evaluate permeability of small molecules across thelipid membranes. We summarize technical developments to estimate the free energy barriers and diffusivities forsmall permeants to go across the membranes. Several simulation results are shown to demonstrate how these meth-ods work. Future direction in this field is also included.

Journal

• MEMBRANE

  MEMBRANE 39 (6), 372-378, 2014

  THE MEMBRANE SOCIETY OF JAPAN

Keywords

• permeability
• lipid membranes
• free energy calculation
• molecular dynamics simulation

Details

• CRID: 1390001206423801216
• NII Article ID: 130005069452
• NII Book ID: AN0023215X
• DOI: 10.5360/membrane.39.372
• ISSN: 18846440
• ISSN: 03851036
• NDL BIB ID: 025922453
• Web Site: http://id.ndl.go.jp/bib/025922453
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I025922453
• Web Site: https://www.jstage.jst.go.jp/article/membrane/39/6/39_372/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2015086716
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed