Magnetic Resonance Microscopy of Chemically Fixed Human Embryos at High Spatial Resolution

• OTAKE Yosuke

  Institute of Applied Physics, University of Tsukuba

• HANDA Shinya

  Institute of Applied Physics, University of Tsukuba

• KOSE Katsumi

  Institute of Applied Physics, University of Tsukuba

• SHIOTA Kohei

  Congenital Anomaly Research Center, Kyoto University Graduate School of Medicine

• YAMADA Shigehito

  Congenital Anomaly Research Center, Kyoto University Graduate School of Medicine

• UWABE Chigako

  Congenital Anomaly Research Center, Kyoto University Graduate School of Medicine

Abstract

We acquired magnetic resonance (MR) microscopic images of chemically fixed human embryos of Carnegie stages 16 to 22 with a large image matrix (256 × 256 × 512) using an MR microscope that we developed with a 9.4-tesla vertical wide-bore superconducting magnet and a dual-channel receiver system to extend the dynamic range of the MR signal. The images showed clear anatomical structures at spatial resolutions of (40 µm)³ to (60 µm)³. We concluded that the experimental technique we developed will aid construction of the next anatomical database of the collection of chemically fixed human embryos.

Journal

• Magnetic Resonance in Medical Sciences

  Magnetic Resonance in Medical Sciences 14 (2), 153-158, 2015

  Japanese Society for Magnetic Resonance in Medicine

Keywords

• anatomical database
• human embryo
• MR microscopy

Details

• CRID: 1390001205196794752
• NII Article ID: 130005069927
• DOI: 10.2463/mrms.2014-0034
• ISSN: 18802206
• ISSN: 13473182
• PubMed: 25740236
• Web Site: https://www.jstage.jst.go.jp/article/mrms/14/2/14_2014-0034/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2016153885
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed