Current use of silkworm larvae (<i>Bombyx mori</i>) as an animal model in pharmaco-medical research

DOI PubMed 被引用文献7件 参考文献19件 オープンアクセス
  • Nwibo Don Daniel
    Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
  • Hamamoto Hiroshi
    Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
  • Matsumoto Yasuhiko
    Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
  • Kaito Chikara
    Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
  • Sekimizu Kazuhisa
    Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo Genome Pharmaceuticals Institute

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抄録

We advocate the use of silkworm larvae, Bombyx mori, as an animal model for discovery of drug candidates. We have established several disease models using silkworms, which offer technical advantages in drug development and the study of host-pathogen interaction. This mini review briefly describes recent trends in the use of silkworm larvae as a non-mammalian model for drug discovery and it offers suggestions regarding the potential for silkworm use in pharmaceutical-biomedical research.

収録刊行物

  • Drug Discoveries & Therapeutics

    Drug Discoveries & Therapeutics 9 (2), 133-135, 2015

    特定非営利活動法人 バイオ&ソーシャル・サイエンス推進国際研究交流会

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