Current use of silkworm larvae (<i>Bombyx mori</i>) as an animal model in pharmaco-medical research
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- Nwibo Don Daniel
- Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
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- Hamamoto Hiroshi
- Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
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- Matsumoto Yasuhiko
- Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
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- Kaito Chikara
- Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
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- Sekimizu Kazuhisa
- Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo Genome Pharmaceuticals Institute
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抄録
We advocate the use of silkworm larvae, Bombyx mori, as an animal model for discovery of drug candidates. We have established several disease models using silkworms, which offer technical advantages in drug development and the study of host-pathogen interaction. This mini review briefly describes recent trends in the use of silkworm larvae as a non-mammalian model for drug discovery and it offers suggestions regarding the potential for silkworm use in pharmaceutical-biomedical research.
収録刊行物
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- Drug Discoveries & Therapeutics
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Drug Discoveries & Therapeutics 9 (2), 133-135, 2015
特定非営利活動法人 バイオ&ソーシャル・サイエンス推進国際研究交流会