Pulmonary Metastasis of Combined Hepatocellular and Cholangiocarcinoma: A Unique Radiographic Presentation with Air-space Consolidation Masquerading as Pneumonia and Primary Pulmonary Adenocarcinoma

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Author(s)

    • Ishii Takashi
    • Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Japan
    • Goto Yasushi
    • Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Japan
    • Matsuzaki Hirotaka
    • Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Japan
    • Ohishi Nobuya
    • Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Japan
    • Sakamoto Yoshihiro
    • Hepato-Biliary-Pancreatic Surgery Division and Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Japan
    • Saito Ruri
    • Department of Pathology, Graduate School of Medicine, The University of Tokyo, Japan
    • Matsusaka Keisuke
    • Department of Pathology, Graduate School of Medicine, The University of Tokyo, Japan
    • Shibahara Junji
    • Department of Pathology, Graduate School of Medicine, The University of Tokyo, Japan
    • Nagase Takahide
    • Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Japan

Abstract

Lung metastasis showing radiographic findings of air-space consolidation is considered to be rare. This report describes the case of a man with progressive left lower lobe air-space consolidation with a history of hepatocellular carcinoma. The pulmonary lesion was initially suspected to be infection and later clinically diagnosed as primary adenocarcinoma of the lung. Although the patient was treated with systemic chemotherapy, the disease progressed very rapidly. A postmortem examination revealed that the alveolar spaces were filled with neoplastic cells subsequently proven to be metastases of combined hepatocellular and cholangiocarcinoma.<br>

Journal

  • Internal Medicine

    Internal Medicine 54(11), 1389-1392, 2015

    The Japanese Society of Internal Medicine

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