Complementary Use of LC-ICP-MS and LC-ESI-Q-TOF-MS for Selenium Speciation

• ANAN Yasumi

  Laboratory of Chemical Toxicology and Environmental Health, Showa Pharmaceutical University

• NAKAJIMA Genki

  Laboratory of Chemical Toxicology and Environmental Health, Showa Pharmaceutical University

• OGRA Yasumitsu

  Laboratory of Chemical Toxicology and Environmental Health, Showa Pharmaceutical University Department of Toxicology and Environmental Health, Graduate School of Pharmaceutical Sciences, Chiba University

抄録

We demonstrated the complementary use of inductively coupled plasma–mass spectrometry (ICP-MS) and electrospray ionization quadrupole time-of-flight mass spectrometry (ESI-Q-TOF-MS) for the analysis of Se-containing compounds, such as selenate, selenomethionine (SeMet), and trimethylselenonium ion (TMSe), found in biological samples. The sensitivity of ESI-Q-TOF-MS for Se-containing compounds was strongly dependent on the chemical species. ICP-MS exhibited higher sensitivity than ESI-Q-TOF-MS, and had no species dependency. On the other hand, ESI-Q-TOF-MS enabled easy and robust identification of Se-containing compounds.

収録刊行物

• Analytical Sciences

  Analytical Sciences 31 (6), 561-564, 2015

  社団法人 日本分析化学会

キーワード

• Selenium
• speciation
• ICP-MS
• Q-TOF-MS
• selenate
• selenomethionine
• trimethylselenonium

詳細情報

• CRID: 1390282679235694208
• NII論文ID: 130005075709
• NII書誌ID: AA10500785
• DOI: 10.2116/analsci.31.561
• ISSN: 13482246
• ISSN: 09106340
• NDL書誌ID: 026441032
• PubMed: 26063020
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I026441032
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.31.561.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.31.561/fulltext.html
• Web Site: https://www.jstage.jst.go.jp/article/analsci/31/6/31_561/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可