高圧力顕微鏡の開発と生物ナノマシンの運動観察  [in Japanese] Direct Observation of the Motility of Biological Nanomachines at High Pressure  [in Japanese]

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Author(s)

    • 西山 雅祥 NISHIYAMA Masayoshi
    • 京都大学 白眉センター/物質・細胞統合システム拠点 The HAKUBI Center for Advanced Research/WPI-iCeMS, Kyoto University

Abstract

Molecular motor is a typical molecular machinery in which the characteristic features of proteins are integrated; these include enzymatic activity, energy conversion, molecular recognition and self-assembly. These biologically important reactions occur with the association of water molecules that surround the motors. Applied pressures can alter the intermolecular interactions between the motors and water. Here, we describe the development of a high-pressure microscope and a new motility assay that enables the visualization of the motility of molecular motors under conditions of high pressure.<br>

Journal

  • The Review of High Pressure Science and Technology

    The Review of High Pressure Science and Technology 25(2), 126-135, 2015

    The Japan Society of High Pressure Science and Technology

Codes

  • NII Article ID (NAID)
    130005075755
  • NII NACSIS-CAT ID (NCID)
    AN10452913
  • Text Lang
    JPN
  • Article Type
    journal article
  • ISSN
    0917-639X
  • NDL Article ID
    026562710
  • NDL Call No.
    Z17-1589
  • Data Source
    NDL  IR  J-STAGE 
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