当院における腎機能低下患者に対する腎排泄型薬剤の処方実態と課題  [in Japanese] Prescription of Renal Excretory Type Drugs for Patients with Decreased Kidney Function- Actual Situations and Problems to Be Solved  [in Japanese]

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Abstract

薬剤師が介入していない状況での腎機能低下患者に対する腎排泄型薬剤の処方実態を把握し今後の課題を明らかにすることを目的として, ジゴキシン, シベンゾリン, ベザフィブラート, レボフロキサシン, バラシクロビル, ダビガトランの6成分が処方された外来患者を対象に血清クレアチニン, 性別, 年齢, 身長, 体重, 対象薬剤の投与量を後方視的に調査した。その結果, 血清クレアチニンの検査が行なわれなかった処方や過量と判断された処方が確認された。さらに年齢や血清クレアチニンのみで腎機能を判断している可能性が推察されたことから, 腎排泄型薬剤の薬物療法に薬剤師の関与は必要であると考えられた。そのためには, 薬剤部内に腎排泄型薬剤の薬物療法を支援するためのシステムを導入することが必要である。

This study was conducted with a view to improving medication management service by reviewing renal excretory drug prescription practices in our hospital for patients with decreased kidney function without intervention of pharmacists. The subjects were the outpatients to whom the doctors had prescribed drugs containing digoxin, cibenzoline, bezafibrate, levofloxacin, valaciclovir or dabigatran. We retrospectively reviewed their serum creatinine levels, sex, age, height, weight and the amount of the drugs prescribed. It was found that there are cases in which medication had been prescribed without serum creatinine testing or prescribed in excess of the amount needed. Furthermore, there were cases in which the renal function had been judged in all probability by age and serum creatinine levels alone. Based on these findings, we concluded that pharmacists should intervene in pharmacotherapy using renal excretory drugs. For the realization of this, it would be necessary to build a system within the Department of Pharmacy to support the pharmacotherapy.

Journal

  • JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE

    JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE 64(1), 23-28, 2015

    THE JAPANESE ASSOCIATION OF RURAL MEDICINE

Codes

  • NII Article ID (NAID)
    130005087463
  • NII NACSIS-CAT ID (NCID)
    AN00196216
  • Text Lang
    JPN
  • ISSN
    0468-2513
  • NDL Article ID
    026575490
  • NDL Call No.
    Z19-224
  • Data Source
    NDL  J-STAGE 
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