Characteristics of Duplex Microcapsules Prepared from an Alginate-Derivative Polymer via Horseradish Peroxidase- and Catalase-Catalyzed Reactions
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- Ashida Tomoaki
- Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
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- Sakai Shinji
- Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
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- Taya Masahito
- Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
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Abstract
In this study, we investigate the impact of polymer concentrations on the characteristics of duplex microcapsules prepared from an alginate derivative possessing phenolic hydroxyl moieties (Alg-Ph) via horseradish peroxidase- and catalase-catalyzed reactions. Membrane thicknesses increased from 17 to 40 µm with increasing Alg-Ph concentrations from 0.5 to 2.5% (w/v). In addition, the mechanical strength of microcapsules also increased with increasing Alg-Ph concentrations. Shrinking of microcapsules was observed in Dulbecco’s modified Eagle’s medium and simulated body fluid containing Ca2+ (13.1–29.2% reduction in diameter for a 12 d incubation). The diffusivities of dextran (4, 40 or 70 kDa) through a membrane of 2.5% (w/v) Alg-Ph microcapsules were almost the same as those of a 1.5% (w/v) calcium-alginate hydrogel. The results demonstrate that it is possible to tune the characteristics of microcapsule membranes obtained through co-enzymatic reactions to customize the particular applications.
Journal
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- JOURNAL OF CHEMICAL ENGINEERING OF JAPAN
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JOURNAL OF CHEMICAL ENGINEERING OF JAPAN 48 (7), 588-591, 2015
The Society of Chemical Engineers, Japan
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Details 詳細情報について
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- CRID
- 1390282679544492416
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- NII Article ID
- 130005088131
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- NII Book ID
- AA00709658
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- ISSN
- 18811299
- 00219592
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- NDL BIB ID
- 026603318
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed