Prevalence and characteristics of breakthrough pain in cancer patients: a pilot study

  • Kishino Megumi
    Department of Palliative Medicine, Kobe University Graduate School of Medicine
  • Kizawa Yoshiyuki
    Department of Palliative Medicine, Kobe University Graduate School of Medicine
  • Sato Yuko
    Institute of Development, Aging and Cancer, Tohoku University
  • Miyashita Mitsunori
    Division of Palliative Nursing, Health Sciences, Tohoku University Graduate School of Medicine
  • Morita Tatsuya
    Palliative and Supportive Care Division, Seirei Mikatahara General Hospital
  • Hosokawa Toyoshi
    Department of Pain Management and Palliative Care Medicine, Kyoto Prefectural University of Medicine/Pain Treatment and Palliative Care Unit, University Hospital, Kyoto Prefectural University of Medicine

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Other Title
  • 大学病院入院中のがん患者の突出痛の頻度に関する予備調査

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Abstract

The aim of this study was to clarify the prevalence and characteristics of breakthrough pain in cancer patients. We conducted a cross-sectional survey of consecutive patients older than 20 years of age admitted to a University Hospital with a cancer diagnosis Breakthrough pain was defined as meeting all of the following criteria: Pain 1)with background pain present most of the time, 2)which is well controlled, 3)with short-lived episodes of exacerbation. One hundred and sixty-nine patients were recruited and 118(69.8%)completed the survey. Of these 118 patients, 11%(95%CI:7–18%)had breakthrough pain. Breakthrough pain occurred in 23%(14–35%)of patients with cancer-related pain and 29%(17–45%)of patients with pain from the cancer itself. Patients reported episodes occurring up to three times a day,a time to peak intensity of within 5 minutes, and a duration of untreated episodes of up to 15 minutes are 54%(29–77%), 54%(29–77%), 54%(29–77%), respectively.

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