私の脳循環代謝研究への取り組み  [in Japanese] My career in the research of cerebral blood flow and metabolism  [in Japanese]

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Author(s)

    • 飯原 弘二 Iihara Koji
    • 九州大学大学院医学研究院脳神経外科 Department of Neurosurgery, Kyusyu University Graduate School of Medical Sciences
    • 伊達 勲 Date Isao
    • 岡山大学大学院脳神経外科 Department of Neurological Surgery, Okayama University Graduate School of Medicine

Abstract

要旨 私の脳循環代謝研究はくも膜下出血後脳血管攣縮の基礎研究,頸動脈プラークイメージングに関する研究,もやもや病に対する臨床研究に大別される.脳血管攣縮ではhypoxia-inducible factor-1 に,プラークイメージングでは病理組織との比較検討に,もやもや病では後方循環障害に焦点を当てて研究を行った.本論文ではこれらの研究を概説し,現在大学院生と行っている研究について紹介する.脳神経外科手術や日常診療と臨床および基礎研究のバランスを維持しながら,科学的視点を持った外科医としてこれらも邁進していく所存である.

In this article, I introduced my career in the research of cerebral blood flow and metabolism. My works of cerebral blood flow and metabolism were divided into three subjects: the basic research of cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH), carotid plaque imaging, and the clinical research for moyamoya disease. I investigated the influence of hypoxia-inducible factor-1 on cerebral vasospasm using a rat SAH model. As a part of the research of plaque imaging, I performed the comparison study between the images by magnetic resonance imaging and histological sections of carotid plaques. I evaluated the difference of significance of posterior circulation involvement between pediatric and adult patients with moyamoya disease. Some investigations in which I have recently engaged as graduate mentoring were also shown in this manuscript. I think that neurosurgeons should have an emphasis on clinical practice and research work evenly. I hope I will grow as a neurosurgeon on this principled grounds.

Journal

  • Cerebral Blood Flow and Metabolism (Japanese journal of cerebral blood flow and metabolism)

    Cerebral Blood Flow and Metabolism (Japanese journal of cerebral blood flow and metabolism) 26(2), 207-212, 2015

    The Japanese Society of Cerebral Blood Flow and Metabolism

Codes

  • NII Article ID (NAID)
    130005093674
  • Text Lang
    JPN
  • ISSN
    0915-9401
  • Data Source
    J-STAGE 
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