Reduced prevalence of cardiovascular disease and metabolic syndrome-related disorders among Japanese long-term inpatients with schizophrenia
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- Nakamura Dan
- Department of Psychiatry, Showa University School of Medicine
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- Takashio Osamu
- Department of Psychiatry, Showa University School of Medicine
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- Iwanami Akira
- Department of Psychiatry, Showa University School of Medicine
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- Morita Tepei
- Department of Psychiatry, Showa University School of Medicine
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- Ikeda Ayumi
- Department of Psychiatry, Showa University School of Medicine
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- Saitou Kenichi
- Department of Psychiatry, Showa University School of Medicine
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- Hirata Yosihito
- Department of Psychiatry, Showa University School of Medicine
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- Umezawa Kaori
- Department of Psychiatry, Showa University School of Medicine
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- Tamura Toshiyuki
- Department of Psychiatry, Showa University School of Medicine
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- Yamada Hiroki
- Department of Psychiatry, Showa University School of Medicine
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- Tani Masayuki
- Department of Psychiatry, Showa University School of Medicine
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- Inamoto Atsuko
- Department of Psychiatry, Showa University School of Medicine
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- Kato Nobumasa
- Department of Psychiatry, Showa University School of Medicine
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Purpose: Individuals with schizophrenia have a vastly reduced lifespan compared with the general population; comorbid cardiovascular disease (CVD) is the leading cause of death for them. Furthermore, these individuals are more likely to have metabolic syndrome-related disorders (MSDs), which increase CVD risk. We examined the medical records of long-term inpatients with schizophrenia to identify methods for preventing CVD and MSDs.<br>Method: A retrospective survey was conducted on 56 inpatients with schizophrenia. The prevalence rates of CVD and MSDs among inpatients with schizophrenia were compared with Japanese general population data from the 2010 National Health and Nutrition Examination Survey. Then, we compared the variables influencing CVD and MSDs between first- and second-generation antipsychotic drug groups.<br>Results: The prevalences of hyperlipidemia, diabetes mellitus, hypertension, myocardial infarction, and cerebral hemorrhage among individuals with schizophrenia were lower than those among the Japanese general population. This effect is likely attributable to the nursing care offered to individuals with schizophrenia, which includes dietary advice, moderate exercise support, and body weight and blood pressure measurement. Medication did not correlate with CVD or MSD prevalence.<br>Discussion: Long-term hospitalization appeared to be particularly useful in preventing CVD and MSDs; thus, nursing care equivalent to that provided in hospitals can reduce the prevalence of CVD and MSDs among patients with schizophrenia. Antipsychotic drugs might have only a minor influence on CVD and MSD prevalence with reliable nursing care. Japanese psychiatric personnel should attend to outpatients with schizophrenia, as this population is increasing and receives less care than do inpatients.
収録刊行物
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- Clinical Neuropsychopharmacology and Therapeutics
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Clinical Neuropsychopharmacology and Therapeutics 6 (0), 16-27, 2015
日本臨床精神神経薬理学会
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詳細情報
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- CRID
- 1390001205337291648
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- NII論文ID
- 130005095672
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- ISSN
- 18848826
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可