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- TSUKADA Nobuhiro
- Hitachi, Ltd., Research & Development Group, Center for Technology Innovation - Mechanical Engineering
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- ENOKI Hideo
- Hitachi, Ltd., Research & Development Group, Center for Technology Innovation - Mechanical Engineering
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- AKIEDA Daisuke
- Hitachi High-Tech Science Corporation, Optical Instrument Engineering Department
抄録
Axial fluctuations in carrier concentrations cause detection noise during chemical analysis using flowing carrier streams. Here, we report a method of axial mixing using serially cascaded microchannel units with branches and junctions. Two branched channels in one unit differ in liquid residence time, and the time lags between the two branched channels are different for each unit. Each unit decreases the fluctuations in carrier concentration of the frequency associated with the time lag. The branched channels are in the form of spirals to induce the secondary flow that decreases axial dispersion and enhances the cancelling effect of the axial fluctuations from the branched channels. We evaluated the effect of secondary flow on the reduction in axial dispersion as a function of the Dean number in computational fluid dynamics simulations. Axial mixing in the prototype mixer was the most effective at a Dean number of 10. A prototype mixer whose volume was 52.5 mm3 reduced absorbance fluctuations from 27.2 to 5.0 mAU in a 0.1% trifluoroacetate aqueous: acetonitrile stream under these conditions. The frequency characteristics of the reduced absorbance fluctuations were evaluated through numerical simulations within a deviation of 20%.
収録刊行物
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- Journal of Fluid Science and Technology
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Journal of Fluid Science and Technology 10 (2), JFST0012-JFST0012, 2015
一般社団法人 日本機械学会
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詳細情報
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- CRID
- 1390282680221195776
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- NII論文ID
- 130005097338
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- ISSN
- 18805558
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可