Specific Interaction of Phospholipid Polymer with C-reactive Protein

  • Goda Tatsuro
    Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University

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Abstract

The PMBN surface is alternative to cell membranes or lipid layers for revealing activation dynamics of human CRP as well as for quantifying the systemic CRP level in the range from normal to acute-phase conditions. Featuring cutting edge material engineering, the biomimetic interface establishes a new paradigm for molecular science that measure dynamic changes of biomolecular activity in the local tissue microenvironments of inflammation and infection at any time.

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