Regression of Cecal MALT Lymphoma after Antibiotic Treatment in a Patient with <i>Helicobacter pylori</i> Infection

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Author(s)

    • Yuge Ryo
    • Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
    • Kitadai Yasuhiko
    • Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
    • Tanaka Shinji
    • Department of Endoscopy, Hiroshima University Hospital, Japan
    • Uraoka Naohiro
    • Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
    • Sentani Kazuhiro
    • Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
    • Yasui Wataru
    • Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
    • Chayama Kazuaki
    • Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan

Abstract

A 63-year-old man with abdominal discomfort was referred to our hospital. Colonoscopy revealed a hemispherical-shaped protruding cecal mass of approximately 10 mm in size with a normal mucosal surface. Biopsy specimens showed nodules consisting of the proliferation of atypical lymphoid cells. Mucosa-associated lymphoid tissue (MALT) lymphoma was diagnosed based on the histological and immunohistochemical findings. Since upper gastrointestinal endoscopy demonstrated <i>Helicobacter pylori-</i>associated atrophic gastritis, eradication therapy was administered. The cecal mass disappeared completely within three months after triple therapy. Therefore, <i>H. pylori</i> eradication therapy may be a useful treatment option for cecal MALT lymphoma.<br>

Journal

  • Internal Medicine

    Internal Medicine 55(2), 135-139, 2016

    The Japanese Society of Internal Medicine

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