Regression of Cecal MALT Lymphoma after Antibiotic Treatment in a Patient with <i>Helicobacter pylori</i> Infection

  • Yuge Ryo
    Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
  • Kitadai Yasuhiko
    Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
  • Tanaka Shinji
    Department of Endoscopy, Hiroshima University Hospital, Japan
  • Uraoka Naohiro
    Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
  • Sentani Kazuhiro
    Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
  • Yasui Wataru
    Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan
  • Chayama Kazuaki
    Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan

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Other Title
  • Regression of cecal MALT lymphoma after antibiotic treatment in a patient with Helicobacter pylori infection

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Abstract

A 63-year-old man with abdominal discomfort was referred to our hospital. Colonoscopy revealed a hemispherical-shaped protruding cecal mass of approximately 10 mm in size with a normal mucosal surface. Biopsy specimens showed nodules consisting of the proliferation of atypical lymphoid cells. Mucosa-associated lymphoid tissue (MALT) lymphoma was diagnosed based on the histological and immunohistochemical findings. Since upper gastrointestinal endoscopy demonstrated Helicobacter pylori-associated atrophic gastritis, eradication therapy was administered. The cecal mass disappeared completely within three months after triple therapy. Therefore, H. pylori eradication therapy may be a useful treatment option for cecal MALT lymphoma.<br>

Journal

  • Internal Medicine

    Internal Medicine 55 (2), 135-139, 2016

    The Japanese Society of Internal Medicine

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