Long-term outcome of the treatment of parotid gland carcinoma

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  • 耳下腺癌治療における長期治療成績

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Abstract

Background: Preservation of the facial nerve in the treatment of parotid gland carcinoma is controversial. In our institution, the facial nerve is preserved as much as possible.<br>Method: We retrospectively reviewed 59 patients with parotid gland cancer treated between 1997 and 2014.<br>Results: Surgery (n=47), definitive RT (n=5), and CRT (n=7) were performed. Postoperative radiotherapy (RT)/concurrent chemoradiotherapy (CRT) was performed in 32 patients. The 5/7-year overall survival (OS) according to treatment was 78%/69% with surgery±postoperative RT/CRT, 35%/35% with CRT, and 20%/20% with RT, respectively.<br>There was a significant difference in OS and loco-regional control (LRC) between patients with facial nerve palsy (FNP) and without FNP. There were no significant differences in OS, LRC, or distant metastasis free survival between patients with no neural invasion and with neural invasion without FNP treated conservatively.<br>Conclusions: If patients have no facial nerve palsy, the facial nerve should be preserved as much as possible with postoperative RT/CRT.

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  • Toukeibu Gan

    Toukeibu Gan 41 (4), 427-431, 2015

    Japan Society for Head and Neck Cancer

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