血管肉腫の胸水浸潤の診断にセルブロックを用いた免疫組織化学的検討が有用であった一例  [in Japanese] A Case of Angiosarcoma of the Scalp with Invasion to the Pleural Effusion:-Diagnosis by Cytology with Immunohistological Examination  [in Japanese]

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Author(s)

    • 天野 雄介 Amano Yusuke
    • 日本大学医学部病態病理学系病理学分野|独立行政法人地域医療機能推進機構横浜中央病院病理診断科 Department of Pathology, Nihon University School of Medicine|Department of Diagnostic Pathology, Japan Community Health Care Organization, Yokohama Chuo Hospital
    • 辻村 隆介 Tsujimura Ryusuke
    • 日本大学医学部病態病理学系病理学分野|独立行政法人地域医療機能推進機構横浜中央病院病理診断科 Department of Pathology, Nihon University School of Medicine|Department of Diagnostic Pathology, Japan Community Health Care Organization, Yokohama Chuo Hospital
    • 若松 賀代美 Wakamatsu Kayomi
    • 独立行政法人地域医療機能推進機構横浜中央病院病理診断科 Department of Diagnostic Pathology, Japan Community Health Care Organization, Yokohama Chuo Hospital
    • 植村 史子 Uemura Fumiko
    • 独立行政法人地域医療機能推進機構横浜中央病院病理診断科 Department of Diagnostic Pathology, Japan Community Health Care Organization, Yokohama Chuo Hospital
    • 桂 義久 Katsura Yoshihisa
    • 日本大学医学部病態病理学系病理学分野|独立行政法人地域医療機能推進機構横浜中央病院病理診断科 Department of Pathology, Nihon University School of Medicine|Department of Diagnostic Pathology, Japan Community Health Care Organization, Yokohama Chuo Hospital

Abstract

今回,我々は頭皮皮膚原発と考えられた血管肉腫の胸水浸潤例を経験した.症例は70 歳代の男性で,頭部腫瘤を切除され血管肉腫と診断された.術後6 ヶ月後に胸水細胞診が施行され腫瘍細胞は,大小の集塊や,印環様細胞,細胞質内小腺腔構造,細胞相互封入像(Pair cell),および複数細胞からなる細胞封入像(渦巻き様構造)として認められた.免疫組織化学的にCD31,D2-40,Vimentin に陽性であった.上記所見と臨床所見より血管肉腫の胸水浸潤と診断した.

Angiosarcoma is a rare and high-grade malignancy lesion that occurs in the skin including scalp and soft tissues. We present a case of a 70-year-old man who exhibited angiosarcoma of the scalp and was revealed to have metastasis to the lung and the pleura by cytological examination after excision of the lesion. Cytological examination of the pleural fluid showed the following atypical cellular features; signet ring-like cells, intracytoplasmic lumina-like or hobnail cell cluster and a whorl-like pattern. Immunohistochemically, the atypical cells were positive for CD31, D2-40 and vimentin, and negative for CD34, TTF-1, calretinin and CEA. The clinical and cytological findings were consistent with metastatic angiosarcoma. Despite treatments, the patient expired due to respiratory failure, 11 months after the first medical examination.

Journal

  • Journal of Nihon University Medical Association

    Journal of Nihon University Medical Association 74(3), 113-116, 2015

    NIHON UNIVERSITY MEDICAL ASSOCIATION

Codes

  • NII Article ID (NAID)
    130005120295
  • NII NACSIS-CAT ID (NCID)
    AN0018408X
  • Text Lang
    JPN
  • Journal Type
    大学紀要
  • ISSN
    0029-0424
  • NDL Article ID
    026597662
  • NDL Call No.
    Z19-263
  • Data Source
    NDL  J-STAGE 
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